Welsh Government

Brain Repair and Intracranial Neurotherapeutics (BRAIN) Unit


Professor William Gray, Cardiff University
02920 688491


The Cardiff University led Brain Repair and Intracranial Neurotherapeutics (BRAIN) Unit aims to be a UK centre of excellence for delivering novel cell, drug and growth factor therapies to patients with currently untreatable neurological and neurodegenerative diseases such as Huntington’s disease, epilepsy, stroke, Parkinson’s disease and multiple sclerosis. 

Wales has significant strengths in basic neuroscience and experimental medicine research, in stem cell transplantation biology and brain imaging and has attracted considerable industrial investment from the regenerative medicine and medical devices industries.

The BRAIN Unit will bridge a resource gap at the neurosurgical NHS trials support interface, supporting pre-clinical laboratory and imaging validation, first-in-man clinical trials and driving novel therapies onward into clinical practice.

The Unit will:

  • develop new and refine existing systems for delivery of therapeutics into the human brain;
  • develop the appropriate infrastructure for capturing relevant high-quality patient data to measure real clinical and social impact, as well as continuing to support ongoing mechanistic translational research; and
  • build a clinical and health economic outcome, social care and service delivery research portfolio.



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